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SARMs, should you use them?
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Our first caller is Wade from Michigan.
Wade, what's happening?
How can we help you?
I was actually, first of all, I want to appreciate, I want to tell you that I appreciate all
your insight and everything in your podcast.
It's been really very informative for me and I don't know, I can't say enough about you
guys.
You're fantastic.
Thank you.
I was actually inquiring about myostatin inhibitors.
I'm curious about, I know I've done some research on them and I know that there are, or there's
one in particular that has kind of drawn some interest with people.
It's called YK11 and I don't know a lot about myostatin.
I know the antagonist is folastatin in your body and basically if you have lower myostatin
then you're able to produce larger muscle mass.
Can you guys share any insight on that?
You want to look like one of those Whippet dogs, is what you're saying.
Totally, like Flex Wheeler.
Yeah.
Okay.
Here's what's interesting about, well, first off, this is a wonderful example of what the
supplement industry likes to do when science comes out.
Years ago there was kind of this discovery that if you inhibit myostatin, and they did
this pharmaceutically or they did this genetically with animals, you would get this kind of runaway
muscle growth.
There were these really dramatic pictures of mice that had their myostatin inhibited
or cows or dogs and it was like a bodybuilder's wet dream.
It made steroids look like vitamin C in terms of just how-
Absolutely.
It's almost like the holy grail.
It kind of seems that way.
It's crazy.
Now, here's the problem.
The problem is the supplement industry saw this research and they quickly went into how
can we market supplements that will promise to do the same thing.
So far, okay, now here's the truth.
Creatine inhibits myostatin to a degree, leucine, amino acid leucine, can inhibit it to a degree.
Resistance training will inhibit myostatin to a degree.
Anything that helps promote muscle growth will inhibit myostatin to a degree.
Is there anything out there legally available that will inhibit myostatin anywhere near
the neighborhood of what the studies done on animals showed?
No, there's nothing that comes even close to that.
Now, you just referred to a selective androgen receptor modulator, like a research chemical.
Correct, yeah.
And it really, it's inhibition of myostatin is similar to what you'd find by taking anything
that activates the androgen receptor, like testosterone or an anabolic steroid.
My firm belief around SARMs is they're not researched very much.
They're not approved for human consumption.
We don't know what they do long-term, and if you're going to go that route, if you're
going to use something that's not approved for human use, and I'm not recommending you
do this either, but if that's the direction you go, you're much better off getting yourself
some anabolic steroids or testosterone because they've been around forever.
We know what they do.
We know what they don't do.
SARMs, we're still kind of up in the air, and I have yet to see any SARM that even comes
close to what like testosterone would do.
But besides that, it really, there's nothing natural on the market that's going to do it.
Like I said, creatine, working out, but there's really nothing you're going to take naturally
that's going to do anything that's substantial.
Didn't we even speculate for a while, like there was a lot of bodybuilders going to Kuwait
and then coming back just insanely jacked, and we asked Ben Pekulski about this, right?
And he just exclaimed that they had everything dialed in like to a degree where their food
was all prepped for them, their sleep was all regimented, their pharmaceutical grade
testosterone was like one of the best around.
So it was literally, they just like stacked everything perfectly in that environment.
Yeah.
I mean, again, I would stay away from any SARM or anything that's really not approved.
These are kind of experimental pharmaceutical drugs.
Some of them that people were using early on, now we're finding, oh, probably not great
for your liver or can cause issues with your vision or cancer.
So I would stay away from them.
And again, if you're going to go that route where you're going to start experimenting
with pharmaceuticals, I mean, testosterone and anabolic steroids have been around for
decades.
We know what they do and what they don't do.
You're better off and they're going to give you better results.
But I don't even recommend, obviously I don't recommend that either.
As far as natural supplements are concerned, nothing's going to do anything.
Wait, wait.
Are you in our mind pump hormones group by chance?
Am I what?
We actually have a mind pump hormones group.
Are you in that by chance?
No, I'm not.
No.
Okay.
It's a free group.
It's on Facebook.
You should totally join it.
This is, there's great, there's great conversation around SARMs and testosterone and all that
stuff.
Really smart people in there.
Yeah.
No, we have two brilliant doctors, hormone doctors in there.
So the grape and they, they actually twice a month go on and do live Q and A's where
you could ask them anything you want.
And they're, they're answering everybody that's in the audience.
So super valuable, totally free to you.
I would recommend doing that.
And you can also always rest assured that if there's something that, that's this groundbreaking
that comes out and hits the market, you'll hear it on here probably first.
I mean, the amount of Sal is, Sal's on every, you know, a deep web, a black market, you
know, supplement forum that exists.
And he's always scouring the internet for what's the latest and greatest and coming
out.
And he normally like a Guinea pig will test himself.
So we'll definitely, we'll be on the front end of anything that comes out.
And I promise that we'll let our audience know if, if anything worth trying or taking
hits the market.
And Wade, this is a hundred percent, right?
If a true effective myelostatin inhibitor comes out like one that really inhibits myelostatin,
not one that inhibits it kind of like, you know, like on the, like as a side effect,
like creatine or whatever, but one that really does an effective job, we will all hear about
it because it will be, it will, it will, it will make anabolic steroids obsolete.
Literally, you'll see 300 pound, you know, point guards in the, in the NBA.
It will be like nothing like we've ever seen before based off of these, you know, initial
animal studies.
By the way, there's, there's side effect myelostatin exists for a reason.
So it's not like it'd be this panacea where you take it and, Oh, I build muscle, no side
effects.
It's probably, it's probably going to come along with its own issues, 20 years off your
life, maybe, right.
Or your heart gets all big too, or something like that.
So hope that helps you.
Right.
Well, I do, I do know that there is one, um, when they, when they actually tested the mice
that there were some issues with their tendons and bones as well, you know, cause your body
kind of naturally regulates itself to the point to where your tendons and bones can
actually hold that amount of mass.
Yeah.
And even look at, even with anabolic steroids, you'll see people take high doses and the
muscles will grow much faster than the support system.
So you'll see tears and issues, um, in muscle tears or tendon tears or ligament tears because
those parts of the body take longer to build and to strengthen.
So, but besides that, there's other side effects, right?
There's other things that we start to see down the road, but I mean, again, testosterone
and anabolics, I mean, testosterone, obviously it's what we already produce.
Like some of the old school anabolics that have been around, I've been around since the
fifties, sixties, you know, like they haven't really come out with any newer ones in a
long time.
And we know what they do and what they don't do largely because they've been around for
a long time.
These SARMs, I mean the one you mentioned, I don't think there's a single human study.
Like so.
No, there, there is.
And I, I did a lot of research on that.
There's a, there's one other guy that, uh, did a podcast on it.
It was like 18 minutes long.
It was pretty extensive research, but, um, there's really no human study at all.
No.
And, and, and, you know, just cause something, you know, attaches to the androgen receptor
and we think, oh cool.
You know, it's going to activate these anabolic androgenic responses and it's going to take
away the, you know, maybe the negatives of testosterone.
We don't know.
We don't know what they do longterm.
We don't, we don't know yet.
So until that, until we know, I'm not going to recommend, I'm going to tell people to
stay away.
Right.
Absolutely.
A hundred percent.
All right.
Thanks Wade.
Thank you.
Yep.
Yeah.
Um, yeah.
I mean, it's, it's fun.
We do look at all this weird, crazy stuff, but, uh, and I get it like, you know, I'm,
this is coming from me.
Uh, but you know, be careful because you don't want to, I remember there was one, so I don't
remember the name of this arm.
I forgot what it was, but I remember people were right.
We're writing in the forums.
This is what I was reading about.
I mean, years ago when they first came out and people were like, yeah, it's really cool.
But after about six weeks you start to lose, no, like you start to lose your night vision
at night.
It's harder to see.
I'm like, what the hell?
That's not good.
Yeah.
But I gained five pounds of muscle.
Oh yeah.
If you can't see it, who cares?
You know what I mean?
Yeah.
No, it's, you know, it's, uh, SARMs are like super, I mean, they've been popular since
we've been talking about it, right?
Like I remember when it first came on the scene, but it ain't slowing down and there's
start, there's people that have podcasts dedicated to it now and that's all they talk about and
people hustling.
You know, it reminds me of, you know, this cause you were in the cannabis market.
Do you remember how popular synthetic, uh, like cannabinoid, you remember like spice
or whatever?
Oh yeah.
And then kids were overdosing and ----.
Like you can't overdose on weed.
They're turning to zombies.
But why?
Cause it was legal.
You know, because SARMs are available online.
Yeah.
That's why they're popular.
Cause they don't even do what testosterone does.
They don't even come close.
The only reason why people are using them is because they're afraid to go buy black market
anabolic.
And that's the part that's so funny.
I mean, I get it though because I was a, uh, I was a young 20 year old kid who was thought
the same thing too.
Like I was willing to take every experimental thing as long as it wasn't steroids.
Cause then I could say I didn't, I never touched steroids and never touched steroids, but it's
like I'm trying all this other stuff.
I just did all the rejects.
Yeah.
All the, all the stuff that's as dangerous, potentially more dangerous.
And they sell you on the idea that they're not.
And so it's like, oh man, bro, that mentality is why I use like super draw meth or master,
like all these pro hormones turned out to be designer steroids.
So it's like waste of time.
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