13 Signs of HEART DISEASE You Can See Doctor Explains

Biologists and Doctors
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10 Video Views·Apr 16, 2026
Did you know that your skin, nails, eyes, and even your ankles could reveal important information
about your heart? Heart disease is extremely common and it often progresses silently. And
it's not just chest pain and heart attacks. There are many types of heart disease that can take you
by surprise. Today I'm going to show you 13 signs of heart disease that you can see and test on
yourself right now at home. So let's dive right in starting with Frank's sign. This is a diagonal
crease running across the earlobe that could be a sign of vascular aging. The earlobe is a great
place to look for vascular aging because it's a fat-free region of skin that's supplied by tiny
blood vessels. If it's stiffening, wrinkling, and folding prematurely, it's a sign that those tiny
blood vessels may not be healthy. And the concern is if these changes are happening in your earlobes,
then chances are that it's also happening in blood vessels of your heart. But it's controversial
because earlobe creases also are more common as you get older. So when should you be concerned?
In general, it's more concerning if you have deep creases that run all the way across both of your
earlobes. Just remember that Frank's sign is far from perfect. So I personally think of it more like
a conversation starter rather than a diagnosis. Okay, now let's shift our attention to the eyelids.
See these flat yellowish patches near the corners? These are clumps of fat and cholesterol under the
skin called xanthelasma. Basically, when cholesterol levels get too high, it starts to deposit into
your tissues. And then scavenger cells called macrophages start chewing it up. But if they eat
too much cholesterol, they turn into these bloated foam cells. So when you see xanthelasma, you're
actually looking at a cluster of overindulgent macrophages. Once again, the concern is that these
skin findings reflect what's going on in the heart. Similar plaques made of those foam cells can form
in your coronary arteries, slowly growing and blocking off the blood supply to your heart.
That's what happened to this 40-year-old woman who came to clinic with exertional chest pain.
And it did not take long to figure out the cause. She had so much xanthelasma that it almost looked
like she was wearing glasses. We actually call this pseudospectacles. She also had large lumps
on her hands and feet called tuberous xanthoma, which are also formed by cholesterol deposits.
This was caused by a genetic condition called familial hypercholesterolemia
that resulted in extremely high cholesterol levels. And it turned out that she had so much
plaque buildup in her heart by the age of 40 that she required open heart surgery to restore
circulation. And get this, even if you have normal blood cholesterol levels, xanthelasma should never
be ignored because research shows us that you still have a higher risk of cardiovascular disease
and death. So if you see xanthelasma, take it as a cue to talk to your doctor about screening for
genetic conditions and how to lower your risk of cardiovascular disease. While we're on the topic
of cholesterol deposits, another good place to look is your eyes. See the grayish white circle
around this woman's iris? That's called corneal arcus. Almost everyone will develop this as we
get older, but if it shows up before the age of 45, that's a red flag to make sure you get your
lipid levels checked. So as you can see, your skin can tell you a lot about your heart, but it's not
always about cholesterol. These bumps around the eyes are caused by a group of conditions called
amyloidosis. The most common type is AL amyloidosis, where your bone marrow produces a huge amount of
misfolded proteins called amyloid. These proteins clump together and can deposit into the heart
muscle, causing it to become stiff and thick, a condition called restrictive cardiomyopathy. Early
diagnosis and treatment is key. You don't want to wait around for symptoms of heart failure,
which is why identifying these skin findings is so important. Start by checking your skin for
waxy, translucent, firm bumps that you'll likely see around the eyes, ears, and neck. Next, take a
look at your tongue. Amyloid can deposit there too, causing it to grow in size. This is called
macroglossia, and I always look for indentations along the side of the tongue because as it gets
bigger, it presses up against your teeth. And finally, a classic sign to watch out for is raccoon
eyes. This happens because amyloid weakens your tiny blood vessels, so even gently rubbing your
eyes can cause these vessels to break and lead to dramatic bruising like this. Next, let's talk
about livido reticularis, which is a net-like pattern on the skin, which is a sign of poor
circulation. The reddish-blue color of the pattern is caused by constricted or blocked blood vessels,
while the rest of the skin maintains a normal appearance. But it's actually not always a bad
sign. In fact, it's really common to see it in healthy babies or even in young women whose blood
vessels are constricted when they're cold. But the key is that it doesn't cause any pain, and it goes
away when they warm up. On the other hand, it could mean that small pieces of cholesterol plaque in
your arteries have broken off and become lodged in the tiny blood vessels in your skin. This is called
a cholesterol embolism, but that's not the only reason to be concerned. As a rheumatologist,
I'll often see this in life-threatening autoimmune conditions like lupus or antiphospholipid
syndrome. So as a general rule, if your skin takes on this appearance and it doesn't go away when you
warm up, and especially if it causes other symptoms like pain or skin ulcers, you need to talk to your
doctor. Okay, now take a look at these fingernails. Can you see those pulsations? That's called
Normally, your heart pumps blood out to the rest of your body through a one-way valve called the
aortic valve. If that valve becomes leaky, blood flows back into the heart between pumps,
a condition called aortic regurgitation. And when blood flows back into the heart,
it leads to a rapid drop in pressure, which causes these visible pulsations. And it's not just the
nails. You can see these pulsations all over the body. Here's Corrigan's sign, where you see these
dancing carotid arteries. This is Demoucet's sign, where you can see a subtle head nod with each
heartbeat. This is Mueller's sign, where you can see the uvula at the back of the throat pulsating,
which I've got to say is pretty wild. And Lendolfi's sign, where pupils constrict and
dilate with each heartbeat. Left unchecked, aortic regurgitation puts a huge amount of
stress on your heart and can lead to heart failure, which brings us to our next topic.
Heart failure is a state where your heart becomes damaged and it can no longer pump
blood effectively. This can happen if the heart muscle becomes too weak, like after a heart attack,
or if the heart muscle becomes too stiff, like in amyloidosis. Now, one of the most obvious signs
of heart failure is a type of swelling called pitting edema that you can usually find in the
feet and ankles. But don't be fooled. This doesn't always mean heart failure. In fact, these days,
I can even get some pitting edema by the end of the day if I don't wear compression stockings.
Fortunately, that's not because of heart disease, but it's because I'm in my third
trimester of pregnancy. Surprise. All right, back to pitting edema. Here's a simple way you can
check for it on yourself. Press your fingertip firmly into a bony area of your lower leg,
either your shin or your ankle for about five to 15 seconds. If this leaves a visible indent
on your skin, that's pitting edema. So why does this happen in heart failure? Well, when your
heart isn't pumping effectively, fluid starts to back up and accumulate in your body. Think of it
like a car accident that causes a traffic jam. You get congestion on the highway, so people start
exiting and going on smaller roads to avoid the traffic. The same thing happens in your body.
If your heart isn't pumping effectively, fluid starts to back up, leading to congestion and
increased pressure in your veins, which then leads to fluid seeping out into your tissues.
Left unchecked, severe pitting edema can lead to skin breakdown and infections, but it's usually
not life-threatening. On the other hand, the main reason that I see patients in the hospital
admitted with heart failure is when fluid builds up in their lungs. It's called pulmonary edema,
and this is what it looks like on a chest x-ray. When your lungs get filled with fluid like this,
the most common symptom is orthopnea, which means shortness of breath that's worse when you're lying
down. It's actually pretty common for patients to tell me that they've started sleeping in a
recliner chair because it helps them breathe better. Fortunately, we have really effective
ways to clear out that excess fluid and dry up those lungs. In fact, in the hospital under close
monitoring, we can use medications to help someone pee out upwards of 10 to 20 pounds of excess fluid
in a matter of days. But heart failure isn't just about fluid leaking into your legs or lungs.
The increased pressure in your veins can also lead to issues with your kidney and liver as well.
I find that people are usually quite surprised to learn that heart failure can lead to cirrhosis
and even liver failure. Now, there are a lot of physical signs that show up when your liver isn't
working properly, from abdominal swelling to skin and nail changes. I've got a whole video dedicated
to exploring those signs in detail, so I'll leave a link below so you can check that out next. Okay,
now for another test. Put the backs of your nails together like this. If you can see a triangle of
light between the nails, that's normal. But if you can't, that's called digital clubbing. It's
most often a sign of chronically low blood oxygen levels, but it can also be from other factors that
stimulate abnormal tissue growth in the fingertips. And there are many causes, from
chronic lung disease to bowel disease, and as you probably guessed, heart disease. The most common
examples are heart birth defects, which are typically picked up in childhood. But when I
see it in an adult, it could be a sign of an infection in the heart called infective endocarditis.
Infective endocarditis usually refers to an infection of your heart valves. If certain bacteria
or fungi end up in your bloodstream, they can latch onto your heart valves and form these little
clumps that we call vegetations. And these vegetations are literally flailing around on
the valve as it opens and closes. So if you're thinking, that looks kind of precarious, you're
absolutely right. Little chunks can break off and travel through the bloodstream until they get
lodged into tiny blood vessels downstream. If they get lodged in the pads of your fingers and toes,
they can cause these painful raised bumps called Osler nodes. Or it can cause painless, flat,
red or purple spots on the palms or soles called Janeway lesions. And perhaps one of the most
recognizable signs is found on the fingernails called splinter hemorrhages. These reddish brown
streaks that look like wood splinters are actually tiny blood clots in the nail bed capillaries.
But seeing a splinter hemorrhage doesn't always mean infective endocarditis. For example,
this person has a splinter hemorrhage from trauma, just hitting their nail against something. And
this person has them from an autoimmune skin condition called psoriasis. In comparison,
infective endocarditis usually causes splinter hemorrhages to form on multiple nails. And you'll
usually have other symptoms like fever, weight loss, or feeling just generally unwell. Now,
when's the last time that you felt your own pulse? Take a moment and check the rhythm.
Does it feel regular and predictable? Or is it completely random? There's one very common form
of cardiac arrhythmia that's so important to detect that many smartwatches are designed to
send an alert if it's detected. It's called atrial fibrillation, and it leads to a random irregular
heartbeat. To understand atrial fibrillation, you need to know that the heart has four chambers,
two ventricles, which are the main pumps, and two atria, which are the primers. They give a
little extra squeeze of blood into the ventricle before it pumps, making it work more effectively.
Now, the atria have pretty thin walls compared to the muscular ventricles. And if you have high
blood pressure, they can get stretched out over time. This can disrupt the electrical system that
coordinates contractions. So instead of the atria pumping in sync with the ventricles,
they just sort of start twitching aimlessly. And without steady contractions, blood in those upper
chambers can become stagnant and form blood clots. And the real danger happens when that blood clot
breaks free, enters the ventricle, and gets pumped out into your circulation. This scenario is far
more common than you might think, and it's one of the major causes of stroke. So if you or someone
you know has an irregular heartbeat, even if it comes and goes, it's something you need to get
checked out. Afib is easy to diagnose on a heart monitor, and treatment with a blood thinner can
dramatically lower your risk of having a stroke. So after hearing all this, if you're feeling
motivated to improve your cardiovascular health, I'd suggest watching these two videos next that
talk about how to lower your blood pressure and cholesterol naturally. As always, stay curious,
stay healthy, and I'll see you in the next video. So bye for now!
