Bio-Rad's Downstream Process Development Support and Services

So can you tell us what you do at BioRag Amplitrees? Yeah, sure. So in short words, I do support customers with whatever needs they have related to chromatography resins we provide. I give them advice and recommendations regarding our resins, our processes and the application that they use. Also, what is the kind of second part of my duties is traveling to customers because we do also support customers on their side. So I do travel doing packings, doing seminars, as well as performing some experimental work in their laboratory if they wish us to do so. So my work is very complex. I do really enjoy what I'm doing at BioRag, especially the fact that I can have an influence and I can help customers in their work in the downstream purification field. So what downstream process development services can you offer to your customers? Yeah, so we have quite a wide range of services we can provide to our customers. One of them, the most generic is our literature, our internal resources, which we do have on our website and this is available to everyone. And yeah, I advise and encourage all scientists to go there and see if they can learn anything from this literature. The second service we can offer is the simple samples. So samples for resin screening, samples in different formats, from 96 well plates to robo columns, up to like one or five milliliter columns. This is all what we can provide to our customers. They can contact us in order to kind of refine these resins required for screening because they can also leverage on our experience how to approach to the screening. Maybe we can advise or recommend some other resins which can be more suitable. Last but not least is the our application lab, which we have in the Munich area. So for customers, we can do screening studies, process development studies, as well as, I don't know, resin aging studies, whatever customers needs to be performed, it can be done there. So how can you help scientists that are starting new projects or need assistance with their current downstream process? So yeah, I would definitely encourage every scientist to contact us if they have any specific question for the resins or for the development process. As a start, we need to know what is the problem or what is the application. So narrowing down the resin selection for this particular application. The key is to understand what are the customer needs, because every single application is unique and needs to be treated like that. So I would want to learn from the customer what is the specific problem or what is the key element they want to achieve from this purification process and focus on that. So why is it important to screen chromatography resin? Yeah, I believe it's super important to screen chromatography resin for numerous reasons. This is one of the most critical raw materials used in the bioprocess. So it's key to select the right one. By selecting the right resin, you get the most optimal operating conditions for your molecule and therefore your quality attributes are maintained and your product can be released at the end. So it is important to have the best suited resin also for economical purposes, because it can give you higher DBC and therefore the highest productivity. What it earns, it will improve the economics of your process and give you advantages over your competitors.