นักวิทยาศาสตร์ในสหรัฐอเมริกาเพิ่งประกาศว่า พวกเขาประสบความสำเร็จในการใช้ AI สร้างไวรัสที่ไม่เคยพบเห็นในธรรมชาติมาก่อนเป็นครั้งแรก อย่างไรก็ตาม ไม่ต้องกังวลไป เพราะไวรัสใหม่เหล่านี้ถูกออกแบบมาเพื่อโจมตีแบคทีเรีย E.coli สายพันธุ์เฉพาะที่ดื้อต่อยาต้านแบคทีเรียตามธรรมชาติ
การพัฒนาครั้งนี้ถือเป็นก้าวสำคัญในสาขาชีววิทยาเชิงสังเคราะห์ และเปิดประตูสู่ความก้าวหน้าอย่างรวดเร็วในด้านการดูแลสุขภาพของมนุษย์ บางที AI เหล่านี้อาจพัฒนายารักษาโรคที่ร้ายแรงซึ่งไม่เคยมีมาก่อนได้
Recently, scientists in the United States have announced that
They used AI to create a virus never before seen in nature.
Achieved for the first time in history
But don't worry about it.
These newly developed viruses are designed to target bacteria.
E. coli
A species that is resistant only to naturally occurring antibacterial agents.
This advancement clearly marks a significant milestone in the field of synthetic biology.
and opened the door to rapid advancement in human healthcare
Because if they can attack bacteria
E. coli using these viruses created by AI
They must have found a way to deal with other types of bacteria.
Has caused problems for humanity for thousands of years in a very short time.
But if you've already gone through the early 2020s,
You should be able to imagine how this entire story might have ended in disaster.
Therefore, today we will take a look at the details of the virus.
A newly created AI, simultaneously.
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To reach more people's eyes.
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Before delving into the details about this newly created virus
Let's understand the basics behind the system.
What AI are they using to create those viruses?
It is called EVO2 and is a DNA language model.
The largest open source project in biology
Researchers developed an AI program.
This appeared after inputting genetic data from millions of organisms.
Animals, plants, microorganisms, and viruses
For many years, it has been provided to the system.
This is a description of the program in question.
By Professor Patrick Su of Stanford University
The EVO2 model itself was trained using all genomic sequence data.
consisting of 9 trillion base pairs
Covering all domains of living organisms
This could only have occurred as a result of a long-term, large-scale scientific effort.
20 or 30 years
In genetic decoding
These data are used to train the model.
The model will learn the underlying rules embedded within those genetic sequences.
Then apply these rules to create a new DNA strand.
Then we use this technology for editing and modifying DNA.
To conduct the test in the lab
Alright
Just in case you haven't sat in a high school biology class in ages
This is a 30-second rapid knowledge review.
New Kyotai is the fundamental unit that connects together in a chain.
Like letters arranged in different formats
to form a sentence
The letters are A, C, G, and T.
New Kyotai
Several hundred units come together to form something called a gene.
and depends on the alphabetical order
Different genes contain different coding instructions within them.
For use in the production of various types of proteins or macromolecules
Therefore, a large language model for the general public
such as ChatGPT or GOK
Thus, it was created based on data from millions of books.
However, EVO
Received data on different gene combinations, receiving billions of sets
which enables this AI model to learn over time
Which combination of values produces a biologically meaningful result?
But it will merely be a distracting signal in the background.
Moreover, Evo has also learned to predict in a new format.
which means it predicts that
The theoretical convergence of Nukleotide
What might it cause to happen in the real world?
This is the explanation from the ARK Institute
which contributed to the development of the Evo 2 AI model
With the following details:
Through being trained on genomic sequence data from organisms across all domains
Since the genomes of batflies and phages
All the way to plants, all living things, including humans.
Therefore, this model is extremely flexible.
EVO2 not only suggests using it for predicting various things, such as
Identifying only the genotypes that cause disease
It also has high potential for generating new data.
Then, this article also mentions what we have experienced at the beginning of this episode.
With the following message:
One of our most notable achievements is Bacteria.
of Fade that actually works
which is the first group of living organisms to be designed by AI
and verified through experimentation
Custom face creation has the potential to be used for bacterial preservation.
The antibiotic-resistant strain
which represents a rapid advancement over traditional antibiotic-resistant rubber development.
Physical inactivity is becoming an increasingly serious problem.
What they managed to accomplish was
Teaching AI to recognize patterns in DNA structures found in nature
Then, the existing data was used to create a formula for a new type of virus that had never existed in nature before.
For this reason, for a certain period of time thereafter
where scientists can use AI
Create a living organism from life images
One of the simplest types has arisen.
That is known as a bacteriophage.
The name literally means "bacterium eater."
And fundamentally, it's a tiny virus that attacks and destroys bacteria.
Current scientific understanding indicates that
These are harmless to humans, animals, or plants.
But it will focus solely on bacteria, which are single-celled organisms.
This story has been unfolding for some time now.
The scientists conducted experiments on these bacteriophages.
and create a synthesized replacement version instead of the original
Nevertheless
What makes this latest advancement so significant and remarkably innovative
It is the process by which the bacteriophage's DNA completely resynthesizes itself.
It was designed and simulated by AI for the first time.
Before it was truly brought to life in the room.
which means that
This is not merely about copying and pasting data.
This is not just a simple case of naturally occurring virus spread.
In reverse, AI analyzes the genome of a certain virus.
as well as other closely related viruses within the same evolutionary lineage
Then it created a new morphological pattern for the viverran.
which is a form that did not exist naturally before
This is the specific method that researchers use.
They trained the EVO-AI using a type of bacterial phase battery.
including the genus of the closest living relatives of that particular bacterium species, approximately
15,000 species
Then, when the AI model
I am already familiar with the Chinese data on viruses in that family.
The researchers instructed the model to generate new versions of the virus itself.
which is similar to the moment when we enter a command or are ready to provide one
That's ChatGPT.
Then, EvoAI generated a new possible configuration.
700,000 formats
And scientists have selected 285
The format they perceive as having the highest chance of success
Then they synthesized the virome's genome in the real world.
285 items created by AI
Go up to the lab room and carry out the test.
They discovered three species of battery-powered eel.
The natural dismantling of the battery pack of the Veleo phase
But they also tested to see whether
The Battleteleophase created by these AI systems
Can they be used interchangeably? And would you believe that
285 types created by AI from Battlegrounds of the Phases
There are 16 types that assemble to form a fully functional virus.
He destroyed the drug-resistant strain of E. coli.
And that's it—16 previously unknown virus types successfully identified.
It can make bacterial infections.
Naturally, previously it had immunity to the same type of virus.
In the study, these results are presented in the section.
Cyan Magazine
Researchers have measured its size as
It is an exciting demonstration of a concept.
which paves the way for designing even larger and more complex systems
Furthermore, in the article from the Art Institute
Regarding the aforementioned research
Researchers have indicated that there is potential for continued research in this direction in the near future.
With the following message:
Kinetic energy therapy is becoming increasingly effective.
's
In dealing with multidrug-resistant bacteria
Treatment goals in the near future
including the phase specific to plant pathogens
T. whipplei bacteria causing disease
Those of clinical significance in these conditions include
Pathogens causing respiratory tract infections
or another type of belief that causes the plant disease known as Black Broth
Moreover, in the latter part, the potential revenue arising from this discovery
They stated that there is still no clear operational plan.
This is the consent form for the research participants involved in this study.
which is referring to the following issue regarding money:
At this stage, we have no plans to further develop this work commercially.
We are an academic institution supported by your generous donations.
And government-funded capital
It is our responsibility to bring this fundamental technology forward.
As widely as possible, reaching the largest number of people possible.
Applied because it has the potential to bring immense benefits to health and humanity.
By this point, some of you may be amazed by the technological advancement mentioned above.
On the other hand, one might still find it hard not to worry about
Just one more step away from creating a new viral strain.
which could potentially lead to a global pandemic in the future
And you didn't just imagine it yourself.
Because this potential risk is something that the researchers who trained the model
Evo AI is also aware of this.
For this reason, they insisted that
No information about viruses causing disease in humans was entered.
Infect the model with mold immediately.
They only trained it on bacteriophages specific to bacteria.
With the following message:
This operation is carried out under comprehensive and stringent security measures.
Than the standard game that was specified
All experiments were conducted within specially designated biological safety cabinets.
Equipped with specially designated waste disposal procedures.
And the equipment was never removed from the designated controlled area.
We use only non-pathogenic host bacteria, such as
E. coli strain C and other strains
E. coli strains commonly used in the laboratory
To ensure that the original bacteriophage
and the AI-designed bacteriophages
No risk to human health
Then they continued to say further.
Our calculation methodology incorporates inherent safety constraints.
EVO cannot sequence the virus genome in humans.
Due to the presence of intentional training data exceptions
To prevent misuse
Both unintentionally and intentionally, through the deliberate design of pathogens.
Although these reassuring words may bring great comfort
But when one overlooks those certifications altogether
It is still unclear in which direction the situation will develop.
ARK itself acknowledges this issue.
The uncertainty becomes even more apparent when one considers the fact that this is a model.
The following are open-source AIs:
While we continue advancing new innovations
Human safety and ethical use
It is the core essence of ARK's approach.
toward this exciting new technology
Nevertheless, additional work is necessary to improve the consistency of the model.
For continuous biological safety
Due to the successive generations of basic biological models
It will have greater capability.
and ARK
Including our partners, we are all proud to have led these efforts.
The aforementioned concern was conveyed concisely and clearly by
Dr. Ingo B.
From the Center for Health Innovation at the University
Jon Hopping, whose key points are as follows
The existing governance framework is still insufficient for effective oversight.
Creative genomics
The current question is not about genome design.
Will the new virus emerge?
The key issue lies in whether society will establish regulatory mechanisms that facilitate the benefits derived from this.
Alongside prevention
Can it not be prevented from causing serious harm?
What is interesting is that just one month before the information was released
Creating 16 new virus types using AI
The NIH has announced a new policy.
You can view the details on the screen.
This is
Policy for ending high-risk biological sciences research
In particular, this policy will prohibit scientists from conducting experiments.
making the viral particles or biological agents more potent and dangerous
It might be another name for Gain of Function research.
or research enhancing the pathogenicity of pathogens
Here is a portion of the NIH announcement as follows:
Policy No. 9, which covers the entire public sector
Clause 5 has been clearly defined for the first time.
Regarding research aimed at enhancing the capabilities of dangerous pathogens
which could pose a severe threat to the lives of American citizens
and poses a significant risk to the national security of our country
It is truly astonishing to see the ban on this type of research.
The first research on enhancing the pathogenicity of pathogens
This issue is certainly worthy of being thoroughly examined in a separate segment dedicated specifically to it.
Nevertheless, the policy also includes other measures.
Stricter guidelines have been established for the presentation of all biological sciences research.
and aim to strengthen disease prevention measures.
With the implementation of new global constraints
That means, in theory, you will no longer be eligible to receive funding for research conducted in countries such as China.
If the research in question involves illegal matters
If conducted in the United States
One more thing that should be mentioned is
The effectiveness of these measures restricting the use of AI models
It is highly suspicious.
EVO2 is an open-source AI model.
Therefore, anyone
You can use this model to run and generate viruses or bacteria using AI.
Simply enter the Chinese data used for training the arrow.
Then ordered the model to create new formats.
To make these newly created forms of life a reality
I don't just want a lab room.
Those with the potential to synthesize viruses only.
I'm not sure myself.
Feel free to share your thoughts below.
We are heading towards a bright future.
where the AI model
These have treated the illnesses and diseases that have plagued us for thousands of years.
Or will it flip over in the wrong direction?
What can we ordinary people like us possibly do?
Besides watching the events unfold and hoping everything turns out well.
Simply put, this is a very good example of progress.
Which is something nothing can stop.
I think we can manage it.
We'll just have to wait and see where this ultimately leads.
This story still has a slight connection.
About what we used to talk about in the service a long time ago
Probably about a year ago regarding what was being said
The CCP is currently under development.
That is a virus that attacks specific genetic characteristics of humans.
Let's share our thoughts—what do you think about this?
Moreover, if you would like links to research papers of this kind
I will paste it in the description box below.
It's the section located next to the like button to follow.
That's it, services, indeed.
I hope you'll keep rapidly pressing both buttons.
Another issue in the final part here
Which might be somewhat related to these viruses.
If you've ever wondered what happens to us humans after we've passed away
That's a very good question.
I'm sure you've surely wondered about this before.
I myself have always wondered about it too.
Epoch Times
The film titled "Excellent Sign" has just been released, and it's absolutely outstanding.
which presents a visual presentation
A group of people who know what happens after death
At the very least, in their own case.
That is truly surprising.
Because this group of people may fall into a condition known as clinical death.
which means the absence of breathing
No brain activity, and no electrical impulses.
or in a state of severe malnutrition
refers solely to the absence of brain activity
However, no matter which group they are classified into
They revived because the memories of everything they had encountered in the other world were perfectly suited.
Then they brought him to sit down and talk with the media from Epoch Times.
To convey those stories so that we may become aware of them.
Their story is truly amazing.
The music they heard
The influence of music on the world they see
and the dimension through which they traveled
Being taken from one world to a higher world, and then to an even higher one.
The living beings they have interacted with
Including the opportunity to reflect on the story of one's own life.
About their own lives
It is truly an excellent movie.
It was presented in an extremely impressive manner.
Because during the interview
A simulation of a real event was also created.
You can therefore see that they are talking about what.
I suppose those other lands, or those different dimensions, those realms...
This is a fantastic new movie.
with an exploration of a newly emerging field of scientific research related to
NDE or near-death experience
In my opinion,
This represents a highly interesting and significant direction for scientific research.
Because it will bring about a profound transformation in our shared understanding of the nature of life.
I think it's the most important question we as humans need to find an answer to.
And it should probably be something science has recently developed for this purpose, especially.
That is seeking the true answer.
What on earth are these things like?
What is life? Well, this is an excellent documentary.
I highly recommend it!
I kept thinking about it for several days after finishing the viewing.
You can go take a look yourself.
I've pinned the link at the top of the description box below.
I hope you'll try looking at it again. It's called Final Hover.
Technically speaking, I'm already dead.
Yet it felt more real than reality itself.
And feel more alive than mere existence itself.
Thousands of people experienced something great and filled with love.
awaiting on the other side
I am surrounded by countless sentient beings.
Once, I remember, I was someone I once knew in this lifetime.
It's more like light itself.
The light of God
I feel very happy.
It feels as if all the pain in the world is gradually fading away.
These human experiences
What does it mean for our shared spirit?
The more consistent and harmonious our love becomes
How much compassion is there?
The more we align with the essence of the universe, the more we resonate with its true nature.
See you again next time.
Roman, the host from Epoch Times
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