Andrew Huberman, Ph.D., is a neuroscientist and tenured Professor in the Department of Neurobiology at the Stanford University School of Medicine. He has made numerous significant contributions to the fields of brain development, brain function and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills and cognitive functioning.
Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award in 2017, given to the scientist making the most significant discoveries in the study of vision. His lab’s most recent work focuses on the influence of vision and respiration on human performance and brain states such as fear and courage. He also works on neural regeneration and directs a clinical trial to promote visual restoration in diseases that cause blindness. Huberman is also actively involved in developing tools now in use by the elite military in the U.S. and Canada, athletes, and technology industries to optimize performance in high stress environments, enhance neural plasticity, mitigate stress, and optimize sleep.
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals including Nature, Science, and Cell and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab Podcast. The podcast is frequently ranked in the Top 25 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.
Hello, and welcome to a special episode of After School.
I'm Andrew Huberman, professor of neurobiology
and ophthalmology at Stanford School of Medicine.
I'm also the host of the Huberman Lab Podcast,
a weekly podcast focused on science
and science-based tools for everyday life.
Today, you're going to learn about practical tools
for optimizing your morning routine.
So without further ado,
practical tools for optimizing your morning routine.
There are certain foundational behaviors,
do's and don'ts,
that set the stage for you to be better at everything.
So a lot of times people will say,
how can I lift more, focus better, remember things better?
It's like, well, let's think about the foundation of that.
And that's always going to come back to two elements,
and that's sleep and what I call non-sleep deep rest.
So sleep is the fundamental practice
or part of our 24-hour cycle,
where if you don't get it on a consistent basis,
you are down-regulating your ability to do everything.
Metabolism is screwed up,
immune system is screwed up, et cetera, et cetera.
However, it is not the case
if you get one night's bad sleep
or that if you're not sleeping perfectly
that you can't perform well.
But let's talk about sleep and just,
because I think it's important.
The goal for most people,
unless you're pulling vampire shifts on deployment
or you're a shift worker, and thank you shift workers,
we'll talk about shift work.
You should try and get really good sleep 80% of the time,
80% of the nights of your life.
The other 20%, I hope you're not getting good sleep
for good reasons that you enjoy.
But the point is that there are a couple things
that you can do.
First of all, every cell in your body
has a circadian rhythm,
meaning every cell has a 24-hour circadian clock
that's regulated by genes.
Think of your body as a bunch of millions of clocks
and you need to align those clocks to a single time.
This is why when you travel overseas,
your gut goes off or it's more easy,
more easily, you get sick
or your thinking isn't quite right.
The clocks aren't in alignment.
They're not entrained, as we say.
Number one practice for everything, sleep especially,
is try and get some natural light in your eyes
within an hour of waking up.
If you wake up before the sun,
turn on a bunch of bright lights
and then get sunlight in your eyes once it comes out.
If there's dense cloud cover,
there are still more photons,
light energy coming through that cloud cover
than there are coming from artificial lights.
So try and get five to 10 minutes
without sunglasses outside in the morning
once the sun is out most days, if not all days.
This has an outsized effect on a number of things.
First of all, it modulates the timing
of what's called the cortisol pulse.
Once every 24 hours, you're gonna get a boost in cortisol,
big spike in cortisol.
It's a healthy boost.
It sets your temperature rhythm in motion,
sets your level of alertness,
your level of focus and your mood.
You want that cortisol pulse to happen
as early in the day as possible.
What's triggering the cortisol pulse?
The cortisol pulse is naturally entrained
by these genetic programs to happen once every 24 hours,
but light will anchor it to the period
where you see bright light.
Got it.
A late shifted cortisol pulse.
So imagine the kid that wakes up
and spends the morning in bed
or you're spending the morning in bed
and you're texting or you're indoors
and you're typing on the computer.
That's not enough light to accomplish
what I'm talking about.
And then you go outside around noon or one,
you're in what's called the circadian dead zone,
which is the time in which light arriving at the eyes
can do certain things, but it can't time this pulse.
That means that cortisol pulse
is going to come in the afternoon,
which means that your temperature rhythm
is going to be shifted late.
And that's actually a signature of depression and anxiety
and difficulty falling asleep.
Many people are waking up
and they're just spending time indoors
and they're putting on sunglasses,
getting in their car and driving,
or there's cloud cover and they think there's no sun out.
I don't mean that you actually have to stare at the sun,
never stare at any light so bright it's going to damage you.
Please don't.
And blink as necessary.
But the indirect rays from the sun
trigger these cells in the eyes
called melanopsin ganglion cells.
These ganglion cells, these are neurons.
They send a signal to your hypothalamus.
Then the hypothalamus releases this peptide,
which is a wake-up signal for your whole brain and body,
and sets a timer for the onset of melatonin release
16 hours later.
Melatonin being the hormone that makes you sleepy
and makes you want to go to sleep.
So you can imagine what happens
if you don't get that light until a few hours later,
everything's shifted.
And then you want to go to,
don't know why you're wide awake at 1130 or 12
and everything's messed up.
The other thing is that you can get bright light
from electronic devices early in the day,
but it's not enough.
You need photons from sunlight.
Now, if you live in Scandinavia in the depths of winter,
if you're up in like Trondheim or Aarhus or something like,
okay, fine, don't buy an expensive daytime simulator.
Get one of these LED light boxes for drawing.
They're very inexpensive in comparison.
You can find them on Amazon.
I don't have a relationship to any of these brands,
but they're easy to find, 20, 30 bucks.
Put that on your desk and just look at that thing
for a few minutes in the morning.
Not as good, but better than being in the darkness.
Then when the sun's out, get outside.
Now, this is a huge, huge effect for the following reason.
The signal that arrives from the eyes to the hypothalamus
also triggers the release of the neuromodulator dopamine.
We hear about dopamine as a feel-good molecule,
dopamine, dopamine, dopamine, dopamine hits.
But dopamine's main role in the brain and body
is to drive motivation, craving, and pursuit.
It is not the molecule of pleasure.
It is the molecule of drive.
It is life force.
Dopamine is actually the molecule
from which adrenaline, epinephrine, is manufactured.
And you may notice you said we crave sun.
It also does make you feel good.
Here's why.
If you think about seasonally breeding animals,
let's think about the Arctic fox.
Well, the Arctic fox in winter is white,
but in the summertime has darker pellage.
It actually, there's a pathway going from sunlight
to dopamine to melanin production in the skin and fur.
So animals that transition from light color to dark color,
that's all mediated by dopamine.
Guess what else happens?
The gonads grow.
There are animals that I've worked on in the laboratory
and that also in humans,
it's now been shown in a beautiful study
that people who get 20 to 30 minutes of light on their skin,
this was a study done in Israel,
so they wear an appropriate amount of clothing,
but they're sleeveless, no hat, no sunglasses.
They were told to go outside 20 to 30 minutes
three times a week, just in the sunshine.
Ideally, they wear shorts also.
They measure testosterone and estrogen in men and women.
Significant increases in both.
And all the associated things of increased passion,
blah, blah, blah, blah,
that is what they measured in the study.
Why?
Well, it turns out that light to the eyes,
but also light to the skin, the skin is an endocrine organ.
It's not just something to tattoo and hang earrings from
and put clothing on.
It actually, there's a pathway involving a molecule
called P53 and the keratinocytes are these skin cells
that when sunlight, when UVB,
ultraviolet blue light penetrates the skin
because it can penetrate the skin superficially,
triggers these keratinocytes to stimulate a pathway
that releases dopamine in the brain and body.
So you feel better when you're getting light in your eyes
and on your skin and you're increasing testosterone
and epinephrine and dopamine increase.
That's why you feel good in the summer months.
People in Scandinavia know this.
There's this kind of spring fever.
In the winter months,
you want to go through every bit of effort
to double or triple the amount of time
that you're spending outside in the morning.
So instead of 10 minutes, make it 30 minutes.
We all are familiar with getting sleepy
and falling asleep.
That's the parasympathetic nervous system taking over.
The longer we are awake,
the longer the buildup of something called adenosine
in the brain and body,
and adenosine turns on the parasympathetic nervous system,
suppresses the sympathetic nervous system.
When we sleep, adenosine is pushed back down.
What is caffeine?
Caffeine effectively, through some chemical steps,
blocks the effects of adenosine.
So if you wait, so here's a little trick if you,
that's, I don't like the word hacks
because hacks imply using something
for a purpose it wasn't designed for.
Here we're talking about hardwired biology.
But if you wake up in the morning
and you didn't sleep quite as much as you would have liked,
that means, and you're sleepy,
that means you still have a buildup
of adenosine in your system.
Let's say you immediately reach for caffeine.
Great, you suppress the action of that adenosine
and you will be more alert.
And guess what happens?
Then the caffeine wears off
and the adenosine binds to the receptors
with greater affinity and you have your afternoon crash.
So a practice that's very useful to people
is to delay the intake of caffeine
by 60 to 90 minutes after waking.
Allow the adenosine to be cleared out
because it's not just cleared out in sleep,
it's also cleared out in those kind of sleepy states
of early morning.
So allow it to be cleared out.
The other thing that clears it out, exercise.
So when you get up in the morning,
you're kind of sleepy, I don't want to do this,
I don't want to do this, but you hydrate and train,
you clear out the adenosine.
Now, I like to drink caffeine before I train
or during training.
I'm weak like that.
But for people that have an afternoon crash,
this can have tremendous benefits of,
and maybe start by pushing it out 15 minutes per day.
Most, everyone that does this says,
oh my goodness, I didn't understand why in the afternoon
I'm crashing so hard.
This will really, really help.
So let me ask you this.
I have a sentence for you.
What time do you wake up typically?
Generally between, well, between 4.15 and 4.30.
Okay, so for most people,
it's going to be a little bit later, probably.
But for you, that means, so you're waking up.
If it's because of an alarm, it's because of an alarm,
but if that's your natural wake up time now
without an alarm,
that means that your temperature is starting to rise
at that time.
That's why you wake up.
That temperature increase triggers that cortisol release.
Now, and that's why some people wake up
right before their alarm clock.
It's this cortisol pulse, okay?
And two hours before that,
so for you, approximately 2.30 in the morning
is what we call your temperature minimum.
It's when your temperature is lowest
that it's ever going to be in the 24-hour cycle.
So the way it works is you wake up
because of an increase in core body temperature.
That increase in core body temperature
triggers that increase in cortisol.
And by viewing light at that time,
you entrain, you ensure that it happens
at the same time the next day.
The clocks of your body are matched to this cortisol pulse.
So viewing bright light in the morning anchors it,
when we say entrained,
it through a circuit that involves cells in the eye
and cells in the hypothalamus,
which then talk to the rest of the cells of the body
through a signal, a peptide that's released.
Make sure that the temperature starts rising,
goes up, up, up, up, up, up.
And sometime around two or three in the afternoon,
you're going to hit your temperature maximum.
You might feel a little sleepy at that time,
but that's actually the time in which
all your systems are kind of revving
at the maximum capacity.
And then it's going to start to drop
and start to drop, drop, drop.
Now that drop in temperature eventually will be
a full one to three degrees below
what your temperature maximum.
And that's when you're going to get sleepy and fall asleep.
This is why it's important to keep the room cool at night
to fall asleep.
The goal here is to increase body temperature
in order to be awake
and to decrease body temperature in order to be asleep.
If we stay with those themes,
a lot of this will just fall into bins.
Exercising will increase body temperature
somewhat paradoxically.
Getting into a cold shower or cold water,
everyone says, well, it must make you cold, right?
Well, if you stay in there a long time,
you become hypothermic, right?
But let's remember the thermostat example.
You have a little area in your brain
called the medial preoptic area.
And if you make the surface of your body cold,
guess what happens?
Core body temperature goes up.
So getting into,
so if you're going to do ice baths or cold showers,
you can do, I would say,
do them sometime better than not at all.
There's a beautiful paper
published in the European Journal of Physiology
in the year 2000,
which took people and had them sit.
They actually had them on lawn chairs in water, a pool.
It was a great way to run an experiment.
I would say people ask about cold showers.
There are not a lot of experiments on cold showers
because think about it, it's very hard to control.
Is everyone under the shower the same way, et cetera?
You put someone in water up to their neck,
you know what you're doing.
So it's experimental rigor that drives that.
But they had people get into reasonably cool water,
60 degrees Fahrenheit.
So it's not that cold,
but they had them stay in for an hour.
Or they've had people get into very cold water,
something like 40 degrees, for just 20 seconds.
Now here's what's really interesting.
That shock that you referred to is adrenaline,
also called epinephrine.
And it is released from the adrenals, obviously,
but also from a site in the brain called locus coeruleus,
a little area of the brainstem
that then sprinklers the rest of the brain with epinephrine
and wakes up the rest of the brain.
So that shock occurs in the brain and the body,
and actually the stuff in the body
doesn't cross the blood-brain barrier.
So you're a two-part system.
When those two systems are aligned, it's beautiful.
When those two systems are out of alignment,
that's not good.
So you get into cold water, that's the shock.
For the first 30 seconds,
for most people who are untrained,
your forebrain, which is controlling decision-making,
is basically suppressed in its activity
and other areas are ramped up.
So just know that.
And that's when people get into panic.
Exactly, panic.
Just understand that passes.
Then what happens is when you get out of the cold,
whether or not it's a longer period at 60 degrees
or a short period,
I would hate to hear that people are only doing 20 seconds,
but maybe a minute to three minutes
at 45 degrees or something,
there's a long arc release of dopamine and epinephrine.
That's what was shown in the study, in humans,
because people always go,
well, it's just in mice.
No, in humans.
And that long arc of dopamine
leads to a near doubling or more
of dopamine and epinephrine.
In my colleague Anna Lembke's book called Dopamine Nation,
she works on addiction,
runs our dual diagnosis addiction clinic at Stanford,
she talked about a patient of hers
that basically helped himself get over cocaine addiction
by doing cold baths,
because it was the only thing
that would give him the kind of dopamine release
that even slightly mimicked his cocaine addiction
and allowed himself to wean himself off
with a healthier behavior.
Now, I'm not saying it's the equivalent
of a drug like cocaine,
but I am saying that it's a better decision
than a drug like cocaine for obvious reasons.
So that mood enhancing effect that you feel afterwards,
it's real.
It's based on a real neurochemical effect.
And that dopamine and epinephrine
will combine with the temperature increase
from cortisol, plus light, plus exercise,
all things that increase core body temperature.
Now you've got increased core body temperature,
you created a dopamine release, epinephrine,
you've created a summer month inside your body.
I don't care if you live in Minneapolis
in the depths of winter,
or someplace even as cold as New Hampshire,
you are creating summer in your body by doing that.
Now, if you live in San Diego,
or Los Angeles, or Arizona,
and it's the summer,
and you're staying indoors and you're on your phone,
and you're not doing any movement until the afternoon,
which it's fine to exercise in the afternoon,
I realize there's some important benefits of that.
And you're laying in bed,
or you're just walking around the kitchen,
and you're putting on sunglasses and driving to work,
guess what?
You're creating a Colorado winter inside of your body,
despite the fact that the sun is out.
So if you're wondering why you're slightly depressed,
your metabolism is lower,
your testosterone output is slightly lower
than maybe you'd like it to be.
There could be other reasons too, of course.
But again, we're talking about modulators.
I'm not saying getting sun in your eyes in the morning
is going to make your testosterone perfect.
What I'm saying is you're setting an internal milieu
through things that increase core body temperature,
dopamine, epinephrine.
And that should be done relatively early in the day.
Thank you for joining
for this special episode of After School.
If you'd like to learn more tools for mental health,
physical health, and performance,
check out the Huberman Lab podcast,
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but much of which is distinct
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We are also hubermanlab.com.
That's our website,
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