Friday Favorites: Fasting to Reverse Diabetes

This is part of my ongoing series on fasting for disease reversal. I have a bunch of other videos on fasting already, so go to NutritionFacts.org and plug fasting into the search bar for more. Currently, nearly half a billion adults have diabetes, and a 50% increase is expected in another generation. I've got tons of videos on the best diets for diabetes, but what about no diet at all? More than a century ago, fasting was said to bring about the cure of diabetes, speedily arresting its development and causing complete disappearance of all its manifestations in several days or weeks. Even so, starvation is guaranteed to lead to the complete disappearance of you, if kept up long enough. What's the point of fasting in a way if it's just going to come raging back as soon as you restart the diet that caused it in the first place? Might it be useful to kind of kick-start a healthier diet? Let's see what the science says. Type 2 diabetes has long been recognized as a disease of excess, a disease of the idle rich, by which they mean anyone who doesn't practice sustained vigorous bodily exertion every day and earning enough to regularly eat more than they need. So, diabetes is preventable, but then maybe it's also treatable. If we are dying of overeating, maybe we can be saved by under-eating. Remarkably, this was suggested about 2,000 years ago in an Ayurvedic text. Diabetics were encouraged to live like a saint, walk for, oh, 800 or 900 miles, dig a pond, or live only on cow dung and cow urine. That reminds me of the Rolo diet for diabetes, proposed in 1797, composed of a diet of rancid meat that was on top of the ipecac-like drugs he used to produce severe sickness and vomiting. Anything that produces sickness has a temporary effect in relieving diabetes by diminishing the quantity of food eaten, and his diet plan, congealed blood for lunch and spoiled meat for dinner, certainly had that effect. Similar benefits were seen in diabetics during the Siege of Paris in the Franco-Prussian War, leading to the advice to manger les moins possibles, eat as little as possible. That was formalized into the Allen starvation treatment, considered to be the greatest medical advance in the treatment of diabetes prior to the discovery of insulin. Before insulin, there was the Allen era. He noted reports in the clinical literature of even severe diabetics clearing up on wasting diseases like tuberculosis, so he decided to put it to the test. He found that even the most severe types of diabetes, he could clear sugar from people's urine within 10 days. Of course, that's the easy part. It's maintaining it once you start eating again, for which he stuck to two principles, keeping them underweight and restricting the quantity of fat. A severe diabetic can be symptom-free for days or weeks, but add some butter or olive oil and the disease can come raging back. As I've covered before, diabetes is a disease of fat toxicity. Infuse fat into people's veins through an IV, and by using a high-tech type of MRI scanner, you can show in real time the buildup of fat in muscle cells within hours, accompanied by an increase in insulin resistance. The same thing happens when you put people on a high-fat diet for three days, or even just one day, or even just a single meal can increase insulin resistance within six hours. Acute dietary fat intake rapidly increases insulin resistance, why do we care? Because insulin resistance in our muscles in the context of too many calories leads to the buildup of liver fat, which leads to the buildup of fat in the pancreas, which is eventually what causes diabetes. Type 2 diabetes can now be understood as a state of excess fat in the liver and pancreas and remains reversible for at least 10 years in most individuals. Put people on a very low-calorie diet, 700 calories a day, and fat can get sucked out of your muscle cells, and you get a corresponding boost in insulin sensitivity. Fat is then sucked out of your liver, and if you keep it up, the fat gets sucked out of your pancreas, and if you can catch it early enough, that can mean a reversal of your type 2 diabetes, meaning normal sugars on a normal diet. With a loss of 15% of body weight, nearly 90% of those who have had type 2 diabetes for less than four years can achieve remission, where it may only be reversible in 50% of those who've lived with the disease for longer than eight years. That's better than bariatric surgery, where those losing even more weight only got 62 and 26% remissions. Your forks are better than the surgeon's knives. Here's how much weight you have to lose to achieve various remission rates for those who've had diabetes for an average of three years. Lose about 30 pounds, and most newly diagnosed type 2 diabetics can reverse their disease. So an extended bout of physician-supervised, water-only fasting could get you there, but you have to maintain the weight loss. One of the things we can say with certainty is that if you regain the weight, you regain your diabetes. To bring it full circle, the initial euphoria about medicine's greatest miracle, the discovery of insulin in 1921, soon gave way to the realization that while it was literally a lifesaver for type 1 diabetics, the use of insulin on its own in type 2 diabetics would not be enough to prevent the later onset of complications like kidney failure, blindness, stroke, amputation. So, as argued by one of the most famous diabetes pioneers, Elliot Joslin, self-discipline on diet and exercise, as it was in the days prior to insulin, should be central to the management of diabetes.