How Do Pharmacies Make Money on Cheap Generic Pills?

Sep 2, 2026

How Do Pharmacies Make Money on Cheap Generic Pills?

Medicare paid about $22.50 for an average generic prescription in 2021. The pharmacy that filled it kept $3.87 — and never got to set either number.

This is how generic drug pricing actually works: who decides what your pharmacy gets paid, why the same pill costs different amounts depending on how you pay, and how a system built by pharmacists in the 1960s ended up squeezing them.

Sources: JAMA Health Forum, FTC Interim Staff Report, USC Schaeffer Center, RAND, Health Affairs.

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