Botox beyond wrinkles: Leslie Fletcher talks lesser-known uses

Fox - LA
13 followers
Oct 26, 2026
Botox injections may be best known for smoothing the face,
but some providers are using it for so much more.
Most of us know it can soften frown lines, forehead lines,
and crow's feet, but there are lesser-known uses.
They go way beyond wrinkles here, and many are considered off-label.
So here to explain what's established
and what's still being studied is our plus-one-of-the-day,
board-certified nurse practitioner, Leslie Fletcher.
Welcome.
Thanks for having me.
You're incredible.
You really are.
thank you thank you we really are and we don't know
the half of it in terms of what botox is
used for everyone says okay it's used for wrinkles
but there's so many more ways that
you're using botox or you're teaching people to use botox as well
so let's go through some of
these and the ways they're being used
so what does off label mean in terms of the way it's being
used okay so off label are basically any area
that the pharmaceutical companies haven't gotten
FDA approved for that specific indication yet and I think we have a
graphic coming up of all the different off-label
and investigatable uses and
some that are they own patents
for but for cosmetic use there's four areas on
label which is the frown
which we're used to seeing right the forehead lines
the horizontal lines and the crow's feet
or lateral canthal lines and then the
newest one is the neck the platysma the neck bands
and that is the first time
any country has approved a lower face cosmetic use
but you're seeing this
graphic as you were mentioning look
at all the areas on the body that you can
use Botox so this came out
in 2017 2014 actually I've just updated it with some
of the newer indications and studied areas
but all of this therapeutic use I
mean those are pretty impressive
so if there's anyone out there that's still a
little nervous about putting it
in the localized frown line look at all the
areas they're using it there.
Right, you're talking about migraine, tennis elbow, joint pain, plantar
fasciitis, excessive sweating,
and a lot of those we do in conjunction with our cosmetic indications
as well. And you said neck injections
or injections right here are the newest. That makes a big
difference. So how does that help? Yeah, so two ways.
So the one that's on label is the vertical
neckline, so those little bands that kind of come from the chin.
Go like this. Yeah, like the E,
you can all see them do it sandra oh okay you must have gotten
your neck injected i haven't i
need to but look at these photos what a difference yeah
so you can smooth that out um using so the
muscle is called the platysma basically the job
of it is to pull the face down so when you relax
the face the lower pole it allows some of the elevators to lift
so there's this almost a
paradoxical lifting effect that we get after we relax
the depressors so it's really amazing
but then you can even take it further you can wrap it around here
for like the little waddle
area which i think you saw that kind of smoothed out the double chin
but you can even take it
further and inject it more superficially
and this is how i love to do it this is kind of one of my
specialized things i trademarked microtox
to do it really superficial it helps tighten the skin
by reducing some pore size oil some secretions some over inflammation
and that pull down that
you're getting with all that fluid that we don't even know
is there the inflammation will actually
allow the face to lift up and you can even smooth out some
of the the glands like the parotid gland
the submandibular gland
and you're actually just smoothing out the inflammation above it but it
shows up like volume in the neck so it does help tighten
and make that neck look nice and lean
are you seeing more men or women come in for that specifically
so the women the neck belongs to the
women it really does i think
when we get our men in it's traditionally going to be kind of that
frown that angry look they want to keep up
with their wives we're hearing that a lot the wives
are looking younger and the men are just kind of aging like
because now that gap is getting a little
bit greater right so oftentimes we'll get men
in for that but i mean there have been some that are
concerned about the neck and the volume
in their neck too as well especially that that parotid
gland slimming is really nice on a man
because it will really chisel out that jawline it makes it
little bit tighter yeah but you know you
can you can kind of mess up the neck a
little bit too if you go to D yeah
so because there have been cases yeah I've
I've had trouble swallowing after I've gotten yes
so really so like you weren't
hospitalized with like a feeding tube
no like a main line no it was it was
literally just like
so tight yeah you can feel a little constriction but that
is depth dependent right
and mostly in the anterior the front part if you're
out here on the sides you don't necessarily get that at all but the
depth is key you have to keep it very superficial so I mean that's why
training is so crucial to me
because these outcomes that you can see or hear
about can make or break it where someone
is too afraid to try it because they
hear oh I might have difficulty that's right yeah yeah
and are you seeing more
and more people turn to Botox for so many
of these treatments yeah I mean
Botox is the gold standard right I mean it's it's
been around since 2002 there
are different types of ones now with different
pharmaceutical companies that have come out with
different ones but it is kind
of the entry-level drug we call it the gateway i know it's an
internal term it's kind of a gateway into all
the services that we offer but i definitely think that
sometimes there are people who are afraid to go like the filler route
or with the ha fillers and
so this is a really great way to try it like
the lip flip that always looks that's a nice way to
kind of see how you would look with a little bit
of volumization in the lip because the the muscle
around the mouth is like a little tightening
so it can tighten tighten and roll in that lip
and as you relax it it allows it to kind of roll out
and gives you just a little the name of it
freaks me out lip flip yeah i just didn't just like well that's freaky
that's what i'm imagining yeah good to know yeah see i live
in the world i've been in this 26 years
so i live in the world where all
these terms we just throw them around like tip dip and lip flip
and all these things. What's a tip dip?
The tip dip is where we can actually inject some
Botox in the tip of your nose.
There's a muscle there that pulls the nose down. So you can
relax that muscle and it lifts the nose up.
Why would you want to tip dip it? You would
want to flip it actually.
So we're doing the tip dip so that it gives a little flip and
gives an upturn. So there's a lot of things we can do to the nose too.
So as you age obviously
collagen is a big, big issue.
So many women take supplements and all of that. But Botox
also can change collagen levels yeah there
are lots of studies on this that
actually shows an increase in pro collagen type 1
which is that collagen
that we need to kind of sustain
the armature of the skin it can actually
regulate even a enzyme
that breaks down collagen it can slow that down so can
actually slow down collagen
and you're seeing here some pictures of a case
report of twins where one twin didn't get Botox
for 15 years think it was and
the other one did this one is actually
a patient of mine who has been getting
Botox consistently for 12 years
and both of those pictures are without toxins so
her skin is better and in better condition 12 years later just from the
Botox so it definitely is a brighter too I mean look
at the shine the reflection
there so that's her raising without any
Botox before we started anything and
And then we have her 12 years later
and six months between her Botox raising there.
So we see it in our clinical photography every day where
a patient's skin actually looks better.
And then partially when we're injecting superficially, we can tighten
that skin, you know, regulate those overactive oil glands.
And so that everything like the makeup just goes on smoother
and it does help build that collagen.
And when you're injecting superficially,
it lasts just about as long as it does for regular Botox.
The duration is strictly related to the dose.
So that happens everywhere,
whether you're intramuscular or whether you're intradermal.
The duration is dose dependent.
So if you're one of those patients that just wants to get a little bit,
don't expect it to last a long time.
We want this to last about three to four months.
We call it a seasonal drug so that you just get it on the season.
So three times a year, it's pretty doable
for most people if you get proper dosing.
and I think that's part of the problem there
are a lot of practitioners out
there that want to look cheaper
so then they under dose and then there are a lot
of patients that are afraid to get
the optimal dosing so they like want to
start slow but then they're not impressed with those results because
they're not getting the full benefits
of it yeah okay I think we're gonna keep
you around if you're around i'm around okay we'll take a break
and then we'll uh we'll continue we
might never let you go we have a lot
of questions i got stuff in my bag you do we want to see
i love it before
and after yeah hi there we're back talking about all things Botox but
predominantly the stuff that people don't know about how Botox
is being used of course with
Leslie Fletcher here the expert
so tell us about how Botox is used for scars because that's really
helpful for people who may need that yeah
so it's used in two ways so a scar prevention is the first
way and that's that's the ideal because
then you want to get that in like within five days of the
injury or the surgery so that when
that wound closes it's closing with less tension oh so yeah
here we have some before and afters of some scars
um so that's the ideal if you can get on it early
but like some of these are we treated even after the fact years later
so because of what we were
talking about earlier with that pro-collagen uptick
and also the relaxation of like there's
a keloid scar coming in here
so sometimes too much collagen is actually not good right it's
unorganized and too much of it
so it regulates either way whether you have too little and there's
a depression or too much
and now there's an elevation as in the keloid scar gotta get that
sweet spot yeah what about like uh things
on your skin like redness oil dark patches yes same same
pathway so that's an inflammatory pathway so you've got rosacea and
melasma those are both inflammatory diseases so if we can bring the
inflammation down by calming down those exocrine glands
which is the oil you've
got the sweat you've got you know some
of those inflammation that's going on in
there that is actually going to help
with flushing and we can see even the
pores this is our pore counter on the left
so those pores are looking less
prominent and there's less there's a less
of them it's yeah it shrinks them because they're
always going to be there but if they're filled
with oil right they're going to be expanded but
if if you can get that oil released and relaxed
then those aren't going to show up as much and
then the same with the flushing you're
not like getting rid of the vessels but you're quieting
the hyperactivity of them and what a lot
of people don't know is that women go through a lot of these
changes because of pregnancy
because of motherhood all of them yeah yeah so i think i have a melasma
before and after there too botox can be used
for molasses yeah wow it is actually we're just
talking about that incredible yeah melasma specifically yes
because it's inflammatory
so it brings down those inflammatory markers
which really helps with the pigmentation
yeah it's a tyrosinase inhibitor
so there are a lot of things that we take or put on topically
that inhibit tyrosinase this is actually
a chemical version of it so we're injecting it
and the duration does last the same as uh botox like the four months
or so with the scars though
sandra this is interesting the scars is actually
um like i want to say curative almost like it
actually controls that collagen you don't have
to keep repeating it with the scars but the melasma
and the rosacea because it's
an ongoing oh there's stop right yeah it takes years i feel
I've tried lasering, I've tried all of it,
like bleaching creams, all of it.
Yes.
I mean, the bleaching cream is the gold standard,
but this is, we actually, the photo I have
is I have her before and then after Botox and then after hydroquinone.
And the bigger change was actually between the Botox before
and after and the hydroquinone.
So yeah.
But lasers are tough with melasma
because that heat can actually activate that inflammatory
cascade.
So we don't want that.
It can work against you, right?
Yeah.
lot about these like what is it like
the lunchtime nose job or whatever people
are calling it right a quick fix yeah
so you're not actually going in and getting
surgery what is that exactly we have
a trademark term nasal tox it's basically
using your your botulinum toxins
or your Botox to inject into areas of the nose
and you can see like pores are reduced
this is six months apart she's flaring
here even some of the little on the talls okay
so that's mine yes that is my
nose and that's yours yeah
so like I have like a little bulbous and well it's
not little but I have a bulbous nose
but I inject it and I've been doing it since
2003 all around to kind of shrink
the oil from there to kind of get rid of
that inflammation because there's not a lot
of space in the nose so any oil is
going to take it and put it out
so the best description of what it can do for
the nose is it's like putting it
in the dryer it makes it smaller smoother less
wrinkles it's a shrink wrap effect
and you inject yourself when you do when you
would do the injections so in 2003
when i did my nose the first time i have to admit i did inject
myself nobody wanted to do it it was not a thing back
then yeah and i i don't have a problem doing
that but um i didn't know to numb back then
but now i do okay okay yeah but not only cosmetically
there are some benefits also using in the nose for snoring
which is huge like a lot of these
these things scarring snoring
and these are game changers for people right yeah definitely so so
the the haytox is kind of how it's colloquially it's called
is where you're actually injecting
inside the nostril into the lower turbine I think I have
a picture up here of a gentleman
that we injected um and it was see how it's like red
and swollen yeah imagine all that constriction
from that inflammation in the airway or the nose passage
and then that's the next morning and you
can see the redness, congestion is gone.
He felt like he could breathe better. We hear a decrease
in snoring. We also hear that from slimming of the neck though,
because if you have a lot of volume
in the parotid and the submandibular glands,
as you sleep, that congestion can be here. So we have
a couple of ways we can help with snoring. Yeah.
And that's for, that's for the patient and their
partner. But for the, for the Haytox, it will help.
It's so crazy. It will help for a chronic
rhinitis so dripping or chronic congestion
so if you're like chronically congested it helps it
opens up the fast way and then if you
were chronically dripping it actually helps turn
off that faucet wow okay this was also surprising
for me pain yes used for pain relieving pain yes
i always feel like my body is broken i know and the older we get
You need a full body.
Inject me all over.
And body talks.
It's very true.
So theratox is the trademark term that I developed.
And another self-experiment,
I had plantar fasciitis in the early 2000s.
And it's fascia.
So a lot of people were telling me,
including my podiatrist, that it wouldn't help.
But I'm like, it has to help
because Botox is like the Windex in my life.
It works for everything.
It's the right of the toughness.
Exactly.
And so I did.
I injected my plantar fasciitis
and so the fascia is inflamed and so at this point now
we know that it brings down inflammation
so any type of myofascial pain that you have
in your body whether it's tennis elbow,
plantar fasciitis, Morton's neuroma, golfer's elbow,
some shoulder pain, trap pain, TMJ,
oh yeah so this is the, we were talking about the
The Pilates stance, and so when we inject sort
of the anterior area of the shoulder
or the pec minor muscle,
it's so tight from all of us kind of just doing this all day
long especially.
Computer the phone.
Yeah, exactly.
And so that, and it's not even a lot of units,
like 30 units, it can just roll that out and
give you this open stance and you feel it almost immediately.
Better posture.
Yeah.
You look better.
Yes, so it's pretty incredible all the different pathways.
This is working on the pain pathways,
so something called Substance P and CGRP, which is all
documented because it's also FDA approved for migraines,
so it works in the same way.
It's working on the pain pathway,
so it's like the inflammation around the nerve, actually,
and so anytime we're doing it in the traps
or any of these other areas of pain of the
body, it works in that same pathway.
Back pain.
Well, yeah, because you know, when you get
bad migraines, it can, like, sometimes the
back of your neck can hurt.
Yeah, exactly.
And that's part of the paradigm here in the occipital area.
It's all connected, yeah.
We have so many muscles in our face
that you don't even realize it until you actually get Botox.
You're like, oh, wow.
Yeah, and each one has a corresponding relationship,
too, which is really another advanced discussion.
It's like when you relax here, you're getting stronger here.
So if you want a really nice brow lift,
really not putting too much in the forehead is the key.
But then you've got to make the patients happy
because they don't want the wrinkles there.
so we have to just dust it a little bit
but then it doesn't last as long there so there's just like
a lot of a lot of working parts to making sure
that we're we're working on those muscles and
their neighboring muscles that actually work stronger
so it is it's pretty fascinating and
it's not as easy as it looks i think that's something
that we're trying to work on as as a
field of medicine is that sometimes on instagram
or tiktok you just see us quickly you know and
it's like oh let's just get a jab here and a jab there
but there's so many different things to
think about like what's going
to happen anticipatory right you have to it's like almost
a blind technique you have to think what's going
to happen two weeks from now what muscles are
going to start working stronger
so it's very complicated well you certainly know your stuff
you're the expert thank you
so much for sharing some of that expertise with us leslie you're
amazing of course if you're curious about any
of these treatments you can find her on instagram
at injectability beauty
and on her website injectabilityclinic.com thank you for coming in
Thanks for having me.
Thank you.
Wealth of information.
Literally talk to you all.
