Don d'ovocytes : le parcours de A à Z – La maison des Maternelles #LMDM

I'm 25 years old, I'm in good health and I decided to donate my blood to the site. On the Internet, I was directed to the closest donation center in my home. I invite you to be donated to the donation center. The first step is to answer a questionnaire about my medical history. And it's not that simple. Familiar antecedents related to your descendants. Parents, grandparents, uncles, aunts, brothers, sisters, cousins and descendants, children, nieces and nephews. Hello? Yes, hello, I'm calling you because I have a lot of questions from a genealogical point of view. Why are you asking me that? Because I'm going to make a donation to your site and I have to answer a questionnaire to find out if there are antecedents in the family. Does your mother know about this? She has to know so that I can give my eggs. No, but it's not going to be your phobia, it's not going to be... Oh, no. No. Not at all. Okay. Go ahead, ask your questions. Spondyloarthritis, ankylosing or polyarthritis, rheumatoid. Did you have that in your family? The only one with polyarthritis is Laurent. So it's my brother. Ah, so there you go. Polyarthritis, rheumatoid. Yes. Fatherly uncle. Thank you for giving me all this information. I'm going to be a grandfather without knowing it. What are you talking about? It's Monday, I'm at the office and I just received a call for all the pre-donation tests. It went super fast because I filled out the questionnaire not even a week ago. And it's becoming very concrete. So obviously, a questionnaire is not enough to give. Second step, a series of medical appointments at the hospital. First interview. Do we start now? Yes, let's go. Thank you. With a biologist. Can you tell me a little bit about how you ended up on this path to become a donor? I come from a family with lots of children and lots of nephews and nieces. And I said to myself that if I really want to have children later and I'm still young, I think I have functional oocytes, so I might as well be able to give them to someone who wants to have children. To be a donor, you have to accept that this personal information, so identity and a whole section on the part of the identifier, is taken in a huge national registry of donors and donors, and in which it will look for the information, the commission of access to the origins, if ever it is requested by a child who will be born from it. Did you know that? Yes, I think it's totally legitimate. I'm going to start with the data of the identifier with you, if you don't mind. This is the data that a possible child can access. Exactly. Your eyes are of what color? Brown. So, I have brown or hazelnut? So, I think it's hazelnut. The color of your skin, you tan a little bit, not too much. Then, I have to talk to a psychologist, but that's confidential. Then, appointment in gynecology. You can put one foot there, one foot there, the buttocks right on the edge. Can I go there? Yes. You will feel that there is gel, it's cold. We look at your green eyes. We see the number of small follicles. If they all grow and are the right size at the time of the function, it gives us an idea of ​​how many ovocytes we can recover. And at home, there are six on one side and a good fifteen on the other. So, that's enough. It's good. You will be able to dress up. Thank you. We're going to make a tree. OK. I have ovocytes, but it remains to be seen if I can give them. Do you remember the questionnaire filled out with my father's help? We go back to each answer and go deeper. What we are looking for is whether there is a risk of severe disease transmission. If so, or at the slightest doubt, we refuse. We are quite strict, in fact, and that's why, in the end, about a third of patients are refused donations. Come on, let's go. Now, it's my blood that goes to the crib. So, how many different labs are there? One, two, three, four, five, six, seven, eight, nine. Nine. I had five, six, nine. Karyotype, hormonal assessment, serology, nine laboratories will therefore uncover the secrets of my body. I am in my crib and I have just received a help from Tenon. We will open it. In the absence of medical, genetic or psychological contraindications, the patient is accepted as an ovocyte donor in the center. You can donate. I have the right to donate my ovocytes? Okay. But now, how does it work? First, congratulations. Thank you. It's good, it's great news, are you happy? Yeah, I wasn't really expecting it. It's stressful, but at the same time, it's a bit exciting. You have a very good reserve, Ariane. Thank you. For us, for us, for us. Okay. In 2022, there were about 990 ovocyte donor candidates. Two thirds were accepted to donate. But it's true that it's below what we need in fertility compared to couples or single women who receive ovocytes. And so we are constantly in tension. As soon as we have a donor who gives, these ovocytes appear directly. How much do you want to donate? It could work to start the stimulation around 29. So the 29th, if we fall on about 12 days of stinging, it would be a function of the week of the 10th. Okay. You will have both injections and both decompressed. Okay. Progestative. Okay. This is where I have to focus. Third step, set up ovarian stimulation. And so, I have to learn to sting myself. We're going to say it's your skin. So it takes either on the sides of the belly or on the top of the thighs. You're going to pinch your skin to make a little cuticle. And you're going to sting right in the middle of this cuticle. And you're going to inject. Go ahead. A little demonstration. And you push. Oh! That's it. So, that's a number. And this is the beginning of serious things. Step 4, start stimulation with a first sting. After a week, we check the evolution of the maturation of my ovocytes. 12. 11 again. 12. It's still a little early, but that's normal. Okay. That's what we're waiting for at this point. Good. We continue the stimulation then, with one sting per day for three days. Second ultrasound, are my ovocytes ready for the gift? Drum roll. That's great. Today is Friday. You come on Monday for the function. Okay. Great. Let's go. A little glimpse of my belly. Eight hours before the function. I feel like it's going to explode. It's been six months since I signed up to give my ovocytes. And it's finally day J, the day of the function. It's the little accessory. Fashion. Thank you. We're going to put you in a gynecological position. I'll explain everything I do anyway. When I sting for the local, etc. We'll show you on the screen. Okay? Okay. So, we're going to start local anesthesia. I'll tell you when I sting and I'll tell you when I inject, okay? Are you okay? Yeah, I'm fine. Breathe in hard. It stings a little bit. It's normal. The effect will dissipate in a few moments. Okay? I'll do it slowly. There you go. So, what you saw appear is my needle. Yes. And I press on a pedal to suck in all the follicular fluid. Okay. There you go. Are you okay? I'm fine. It doesn't hurt? A little, when it feels like pressure. Local anesthesia is good because we can see what we're doing. I admit, I was quite curious to know how it was going. Okay, let's move on to the other eye. How are you? I'm fine. It's perfect. We're very happy. We're going to catch the last ones anyway. It's over, bravo! You were very brave. Thank you. So, either we vitrify, so we freeze the oocytes, or we do embryos. So, on the other hand, we do embryos today. And then we let them evolve for five days. And we only transfer embryos that are five days old. Okay. As a donor, I don't know to whom my oocytes are destined. But I hope they will make families out of them.